I'm going simple, home teams on Saturday (Chiefs and Rams), visitors on Sunday (Chargers and Eagles).

Colts are going to fall victim to Andy Reid after the bye week.
Rams are just plain good, and the Cowboys are a bit more one dimensional than people think.
Chargers are filally good enough to win over the no longer dominant Patriots
Brees is #betterthanbrady, but the Eagles are surging and the double doink is an apt summation of the Eagles season, just good enough to win.